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It sure would be interesting to see what kind of impact a person in one of the non-placebo arms is getting from the drug. Al has mentioned weight loss, fewer hypos, etc. The other thing that will impact the long term success of the drug is how easy is it to titrate. The typical profile of especially type 2 diabetics is non-compliance. If it takes patients a long time to find the proper dose the likelihood of compliance diminishes.
