I believe this is just the SEC's stamp of approval on our S-3 registration statement filed about 3 weeks ago. Now the company is free to go ahead and sell the securities that it registered. Doesn't mean they will, just means they can.
Of course, if MNKD has some sort of deal cooking, and that deal involved issuance of shares, that deal can go forward now, so that might be the reason for the jump in price (which would also strongly imply that the deal isn't a bad one, shareholder-wise). Although it seems like more than a coincidence, I don't think the price job is related, as I don't think the issuance of a Notice of Acceptance by the SEC was ever in serious question, but just a matter of time. So, I don't think the MNKD reaction is "whew, now we can get the deal done!"
Rather, my guess is that whatever it is that has been pushing this stock up for the last several weeks is getting closer and/or hotter, and one would think it has something to do with financing. I assume we'll find out one day soon, but who knows, it could all be a massive head fake!