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Message: Carlton Johnson, Eric Swartz and David Pohl

Carlton Johnson, Eric Swartz and David Pohl

posted on Nov 18, 2009 06:33PM

are all on the BoD for Peregrine Pharmaceuticals. With all this good news, lately, from Peregrine, I wonder if CJ will be making his exit from PTSC before too long.

TUSTIN, Calif., Nov 18, 2009 /PRNewswire-FirstCall via COMTEX News Network/ -- Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM) today announced that researchers presented positive data on progress in its federally funded preclinical viral hemorrhagic fever (VHF) program, confirming that its phosphatidylserine (PS)-targeting antibodies bind to VHF viruses and virally infected cells and increase survival in a model of lethal VHF infection. The data were presented at the 2009 Chemical and Biological Defense Science and Technology (CBD S&T) Conference in Dallas, Texas.

Researchers presented interim data from Peregrine's multi-year program to assess the company's PS-targeting antibodies as broad-spectrum agents for the treatment of viral hemorrhagic fevers, a potential biodefense threat.

TUSTIN, Calif., Nov 10, 2009 /PRNewswire-FirstCall via COMTEX News Network/ --

Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHMD) today announced that a newly published study shows that a phosphatidylserine (PS)-targeting antibody similar to the company's lead product candidate bavituximab demonstrated potent anti-tumor activity when combined with radiation in a model of aggressive brain cancer, doubling the survival time of test animals and producing long-term cures. The study also provides further evidence that the anti-cancer activity of bavituximab and other PS-targeting antibodies reflects multiple novel mechanisms. Bavituximab is currently in Phase II clinical trials for the treatment of advanced breast cancer and advanced lung cancer. The new study is available in the current on-line edition of Clinical Cancer Research(1).

"This important new study provides additional scientific evidence that PS-targeting antibodies, including bavituximab, employ multiple novel mechanisms to mobilize the immune system to combat cancer and that these mechanisms are enhanced by concurrent radiation therapy," said Steven W. King, president and CEO of Peregrine. "The potent anti-tumor effects observed in this study, which used an extremely challenging preclinical model of brain cancer, are very impressive. These results provide a strong rationale for conducting future clinical trials of bavituximab in combination with radiation for the treatment of glioblastoma and other brain cancers."

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