VANCOUVER
This must be the bottem, all the insiders are grabbing their shares at .15.  3M has 
already announced they have started sellling the Ramp flu test, and Roche is sure to 
follow with the cardiac tests in the New Year.  The common shareholder is kind of 
getting shafted with dilution but it looks like the company is going to do well.

~~ Dimar

Response Biomedical Announces Insider Participation in Current Financing

    VANCOUVER, Oct. 27 /CNW/ - In accordance with the Rules of the Toronto
Stock Exchange, Response Biomedical Corporation (TSX: RBM, OTCBB: RPBIF) (the
"Company") today announced that certain insiders (the "Insiders") of the
Company will participate in the financing announced on October 14, 2008 (the
"Financing").
    As previously announced, the Financing involves the issuance of an
aggregate of (up to) 36.67 million units with each unit being offered at a
price of $0.15 per unit and consisting of one common share and one half of one
share purchase warrant. Each full warrant will entitle the holder to acquire
one additional common share of the Company at a price of $0.20 per common
share for a period of 36 months from the closing date of the Financing.
    The following insiders will be participating in the Financing and will be
purchasing such number of units as appears beside their name (representing
such percentage of the total number of issued and outstanding common shares
prior to this transaction as appears in brackets beside the number of units):

    <<
    (1) Richard Bastiani (Chairman):  1,333,334 units (approximately 0.98%
                                      excluding any warrant shares and
                                      approximately 1.47% including all
                                      warrant shares)

    (2) Richard Bear (Director):      666,600 units (approximately 0.49%
                                      excluding any warrant shares and
                                      approximately 0.73% including all
                                      warrant shares)

    (3) Anthony Holler (Director):    1,833,334 units (approximately 1.34%
                                      excluding any warrant shares and
                                      approximately 2.0% including all
                                      warrant shares)

    (4) S. Wayne Kay (CEO) :          670,000 units (approximately 0.49%
                                      excluding any warrant shares and
                                      approximately 0.73% including all
                                      warrant shares)

    (5) Todd Patrick (Director):      670,000 units (approximately 0.49%
                                      excluding any warrant shares and
                                      approximately 0.73% including all
                                      warrant shares)

    (6) Duane Morris (COO):           333,334 units (approximately 0.24%
                                      excluding any warrant shares and
                                      approximately 0.37% including all
                                      warrant shares)
    >>

    The aggregate total number of units to be purchased by the Insiders is
5,506,568, which represents approximately 15% of the aggregate total of (up
to) 36.67 million units being offered under the Financing, assuming that all
36.67 million units are sold. As a percentage of the total number of issued
and outstanding shares prior to this transaction, the common shares being
issued to Insiders represent approximately 4.04% excluding any warrant shares
and approximately 6.06% including all warrant shares.
    As a percentage of the total number of issued and outstanding shares
prior to this transaction, the common shares being issued pursuant to the
Financing (assuming that all 36.67 million units are sold) represent
approximately 27% excluding any warrant shares and approximately 40.3%
including all warrant shares.
    Prior to completion of the Financing, the number and percentage of the
Company's issued and outstanding shares held by the Insiders is as follows:

    <<
    (1) Richard Bastiani (Chairman):  N/A
    (2) Richard Bear (Director):      N/A
    (3) Anthony Holler (Director):    1,647,166 common shares (1.21%)
    (4) S. Wayne Kay (CEO) :          6,700 common shares (0.005%)
    (5) Todd Patrick (Director):      1,158,997 common shares (0.85%)
    (6) Duane Morris (COO):           N/A

    The Financing is expected to close on Tuesday, October 28, 2008.
    >>

    About Response Biomedical