I concur...Why use a word like efficacy otherwise? PPHM is a stock I've mentioned on here before and they halted a phase III trial at the 33% event point.

• The decision to stop the trial was based on the recommendation of the study's Independent Data Monitoring Committee (IDMC) following a pre-specified interim analysis performed after 33% of targeted overall events (patient deaths) in the study were reached. Results of the analysis demonstrated that the bavituximab plus docetaxel group did not show a sufficient improvement in overall survival as compared to the docetaxel group to warrant continuation of the study.

Hopefully the arm taking Apelbetalone is MACE free, or is taking much longer to MACE than the palcebo arms. I do not believe this trial has a control arm....meaning no treatment at all, no statins no RVX 208.

I do know that the so called placebo effect is very real....just taking what one believes to be a drug can have a positive impact on one's frame of mind, and studies show that a PMA enhances immune system response, while being depressed weakens it.

Of course when talking about diabetes and CVD the immune system may not come into play...I don't have enough of a medical background to say.