Hi Bear,
Lets say we're close of the 250 mark (tick tock), divided by 4244 patient years (crude estimate, I know, I know), we're at 5.9% annual average MACE rate? Started at 8, went down at 7 and now close to 6?
Normal because of the higher dosing average, the lower the MACE rate will be because MACE events happen more often close to enrollment.
But, while there is a lot of uncertainty, it can only be good news for BETonMACE.
Bonne chance à tous!