...We Welcome You To The Resverlogix HUB withIn The AGORACOM COMMUNITY!

Free
Message: Re: Futilitcy analysis
4
May 12, 2017 06:14AM

May 12, 2017 08:29AM

Hartland, I will try my best to respond to your questions.

"Did the company over parse  the data to get the RRR." I think the post-hoc analyses for plaque reduction and 5-point MACE were very informative and valid. But it is always going to be difficult to extrapolate incidence of death, MI and stroke in a larger Phase 3 trial in high-risk patients from a 6-month long study in not-as-high risk patients.

"Am I wrong in assuming  the medical community  would have a Predicted number of 3 point Mace in say 1000 patients in one year?If so given they would know the Average patients enrolled, the average time such were dosed,and the number of 3 point events that have occured.Therefore if this has exceeded  the Predicted number this would be positive for Rvx.I know what I am trying to say I hope you do.The longer it takes to get the 125 events would sem to me to be desired (especially  for the patients"

Read my posts in this thread. Lots of info there that goes into detail.

"The Renal delay confuses me as the FDA is onside and the possibility  of success seem high.We need other Irons in the fire." My opinion is that this trial is ready to blast off once funding is resolved, as suggested by Tada here.

BDAZ

 

Share
New Message
Please login to post a reply