I think we've all been there.  

You have all the wood set up, you lean logs against each other teepee style....then you put some twigs at the base and light her up, but it doesn't catch.  So you gather up some dead grass and put the grass under the twigs, thinking "that'll do it"....but the grass is a little damp and so it still doesn't catch.  Maybe you find an old magazine, so you rip that apart and light it up, but its that glossy type of paper and it doesn't burn well either.  

We've had the CKD trial news.....wisps of smoke but no fire.

Pfizer patent news.....more wisps.

Now orphan disease Fabry news...still waiting.

When starting a campfire, or a fire down at the beach.....it eventually gets going.  Somone finds something....dried out newspaper balled up often does the trick.  Sometimes people find lighter fluid and WHOOOOSH, the fire explodes but burns out very quickly....better still are those little white cubes you can buy to get a charcoal bbq going.  

I think the point of this analogy is pretty clear, but I'm going to take it a little further.

The way I see things this isn't some little fire at a campsite, some logs tossed into an old tire rim at some KOA campground. Anyone who's been to Quebec or Acadia knows the fires they set up to celebrate St Jean Baptitse Day.  Logs that are 6' long or bigger are set up like that big teepee.  And when the fire really gets going it can be seen for miles.  

We've got some pretty big logs for our fire, Diabetes, CKD, Orphan Diseases like Fabry and Friedreich's Ataxia, Alzheimer's...these are big long pieces of solid wood that should burn for a while.  And there are more logs to add once the fire is burning.

I'm not one who's gonna walk away, I want to see a pillar of fire burning bright.