Re-posting this after this weekend's big reveal of the CANTOS data. 

A nice visual of IL-1B to IL-6 to CRP courtesy of Ben Smith taken from Figure 5 this article in Circulation Research "From C-Reactive Protein to Interleukin-6 to Interleukin-1" by Paul M Ridker.

"In this review, epidemiologic, genetic, experimental, and clinical evidence supporting this upstream movement from CRP to IL-6 to IL-1 are described, as is the unifying concept of hsCRP as a downstream biomarker for IL-1β activity."