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Message: The last DSMB update of Feb 26th....

Interesting thoughts tada.....especially speculating that the trial may already be enrolled well beyond the 2,400 number required by the trial protocol. 

I'd be curious to know how you arrived at 2,750....it doesn't seem arbritary in any case and it would be an increase of 350 over what we've been told to date, almost a 15% increase above that 2,400 number which strikes me as statistically significant.  

As for the wording of the Feb 26th report, the language certainly lends itself to the expectation of an increase in enrollment.  

We are currently considering the extent to which we enroll beyond 2,400 patients...

However I still see an out if they've decided against substantially increase the numbers....to my mind if they've enrolled say 2,432 (pulling a number out of thin air) for all intents and purposes I would still count that as 2,400.....but 2,750 is a different matter.  

"The extent" I believe could still be 0.  

I view it in similar fashion to the April 17th news about the proposed share offering.  That news was written in such a way that the proposed offering seemed like pretty much a done deal, going so far as to enumerate the ways they were going to be using the funds.

That April 17th PR started out with the word "proposed" but then shifted to more definitive language which I will bold:

The number of Units to be distributed, the price and composition of each Unit, the minimum and maximum size of the Offering, and the exercise price and term of each warrant will be determined by negotiation between the Company and the Agent (as defined herein) in the context of the market with final terms to be determined at the time of pricing.

The Offering will be conducted on a best efforts basis by Bloom Burton Securities Inc., the Company’s agent for the Offering in Canada (the “Agent”). The Units may also be offered for sale in the United States on a private placement basis pursuant to an exemption from the registration requirements of the United States Securities Act of 1933, as amended (the “U.S. Securities Act”) and applicable state laws.

A lot of chatter ensued that basically assumed this offering was pretty much a done deal, and we all now know it was not.

But getting back to the trial....the B&B presentation was back in early May, the 2nd or 3rd going off memory.  So that was over two months after "they were currently considering" the extent (if any) to which they would enroll beyond 2,400 and Don stated during his presentation that at 2,400 they were properly powered. 

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