"IF and only IF it were 4000 as of today,... what could and what would that possibly tell us,...? Much appreciated. Would it say the trial is working,... that RRR is higher than 25%,..?"
It actually wouldn't mean that much. As per my previous post, it seems that reaching 250 events is not the end of trial trigger, they could voluntarily go past 250 before ending dosing, and due to amibuity they may or may not already be at 250 or more events. If we knew the actual number of events to date and the number of patient years, one could compare that to the original projections to determine if things are really taking longer than expected. But you would need both numbers. Even if you had those numbers, the big unknowns of the actual placebo event rate and apabetalone event rate would preclude determining if apabetalone is having an effect on MACE. Sorry to burst your bubble.
BearDownAZ