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Message: Re: Upcoming CVOT results
2
Apr 12, 2019 10:08AM

BearDowAZ,

The 51% and 49% is a pretty high bar set here,... I thought the 25% Amarin was the high mark to beat,...?

The MACE results demonstrated by oral semaglutide were driven by a statistically significant reduction in cardiovascular death of 51% (HR 0.49, p=0.03), while non-fatal myocardial infarction (HR 1.18, non-significant) or non-fatal stroke (HR 0.74, non-significant) were broadly similarly distributed between the two treatment arms. In addition, a statistically significant reduction in all-cause mortality of 49% (HR 0.51, p=0.008) in favour of oral semaglutide was observed.   

Much appreciated!

 

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