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Message: SA blog post for those interested.....

I agree.  For all we know, RVX could come out tomorrow and say 250 is over. Or it could be end of May.  I think predicting MACE rates in a 1,900 patient population at various levels of near death-ness, is very difficult.  Add the fact that we are transitioning from winter to spring in the Northern Hemisphere, and it further complicates such incidence.  

FWIW, I think the more relevant question is what happens once the 250 events are over?  Is there some way that RVX can expedite the adjudication of the last few MACE events: 2 to 3 months.  It has never been clear to me why the last few MACE events should take so long.  

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