Actually based on this presentation  (https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=5&cad=rja&uact=8&ved=2ahUKEwi729OorOzhAhUOmuAKHTa4CCkQFjAEegQIAxAC&url=https%3A%2F%2Fpace-cme.org%2F2018%2F06%2F26%2Fslides-a-clinical-view-on-bet-inhibition-in-ckd-cvd-understanding-recent-data-and-future-perspectives%2F%2Fdownload-slides-a-clinical-view-on-bet-inhibition-in-ckd-cvd-understanding-recent-data-and-future-perspectives.pdf&usg=AOvVaw1jTrbluaMsg3kO3oPmMdU2 ), the change in egfr was non significant. The change in alkaline phopshatase was significant but AP has many different sources. Change in CRP was non significant.