tundup,

When you stated the part below,..

You say the trial started at 8% per 100 patient years and now it is around 7.2% per 100 patient years,.... then you say ORIGINALLY EXPECTED 10%-11% MACE EVENT RATE,... do you mean % rate for the whole trial... ie NOT per 100 patient years,...?  

I recently had the opportunity to catch up with management. Apparently the blinded data is all pointing in the right direction. The rate of MACE events has been dropping steadily since the beginning of the trial, starting off at the expected 8% per 100 patient years but now down to 7.2% per 100 patient years (originally expected to see 10%-11% MACE event rate).