The reason I think the medical profession has so far failed to get behind RVX, is because it upsets the conventional wisdom on medical research.  A seasoned medical researcher is used to thinking of a single molecular target for a single downstream effect.  The idea that a simple molecule can concurrently modulate multiple biological processes, is effectively telling our seasoned researcher that he/she has been going down the wrong research road all his/her career.  That is a very hard one for any human being to accept. 

Physicians are taught to be cautious and medical science wants things to be proven beyond reasonable doubt before practices change, this is not because of human egp but we are treating human bodies and taught above all to do no harm. It is easy to be brave when it is someone else who is paying the price.

I think you are underarating the complexity of the human body, since you cite all these multiple mechanisms can you also tell me  the mechanism by which the molecule only works on severe cases and not the less severe cases?

I am cautiously optimistic but do leave open the possibility of failure in some degree, if you dont feel that way, that is your  right and pregorative.