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Message: Re: Not on the board, nor bored, but on board

Welcome to the board 65jaoya. Yes, a lot of potential indications for apabetalone and other BET inhibitors. Many, but not all, are inflammation related. Golfyeti had a great post a few months back brainstorming some of the potential diseases that apabetalone and or other BET inhibitor studies been studied in (most  pre-clinical). Here's Golfyeti's list.

"Cardiovascular Disease

Chronic Kidney Disease

Alzheimer Disease

DIABETES MILLITUS  (DM)

FABRY DISEASE

COLORECTAL CANCER

LIVER CANCER

HIV-1 (AIDS)

MUSCULAR DYSTROPHY (FHSD)

RESTENOSIS

Osteoporosis

Friedreich’s Ataxia

Pulmonary arterial hypertension PAH

Degenerative diseases of the eye (retinal)

PERIODONTAL DISEASES

NASH (nonalcoholic steatohepatitis)

ASTHMA

Paroxysmal nocturnal hemoglobinuria (PNH)

ARTHRITIS"

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