Just like nearly all studies, you continually learn ... think of all the things that were accidentally invented while exploring "other" hypotheses and theories?
I would imagine the data will be evaluated in many post hoc ways, aside from the primary and secondary end points. The truth is that with success, who really knows what the longer term benefits could be, things we may not have even "contemplated" yet!
First things first, let's get this puppy across the BoM finish line successfully and see what the future brings in this new, fluid, and dynamic area of clinical study.
Btw, aside from 3 point MACE end points, I am also VERY curious to see what 5 point MACE looks like in this particular follow up P3 BoM study, as compared with P2!!