"With median dosing being about 24 months can that help us guesstimate the number of patient years,...?"
2425 patients X median 2 years = 4850 patient years. That's the high side.
But, deaths, discontinuations, dropouts do occur. So let's knock 25% off.
4850 X 0.75 = 3637.5 patient years. That's the low side.
Actual number is probably somewhere in between.
BDAZ