You can pretty much sense that there's some nervousness out there, and of course it's crunch time.  Like others, I also have a few bucks invested in this.  But, I've prepared myself to lose it all (at least on paper) rather than play the panic card and sell to try and beat the rush if this doesn't fly.  We've said this before, but there will be a lot of information coming out of this trial that could help to mitigate any immediate loss that might come from a negative topline.  So, topline is only step 1 and I'll wait until step 2 (Full Data) and see how things go from there.  If nothing else, this will take the pressure off of feeling the need to do something over the next couple of months....other than wait.  But, everyone is different in terms of what their goals and objectives are.  What we do know is that the news will come at any time and it could be great, kind of ok, or not great.  I'm still thinking great because it's better than dwelling on the alternative.  When it's crunch time, you've gotta stay positive.