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Message: Re: Q4 2019 Events
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Oct 25, 2019 09:16AM

Now that we're past the AGM, to close out the Q4 schedule we have ASN, AHA and CTAD. Renal, Cardio, Cognition. Go RVX Go! Note, I have removed BIO-Europe as a potential event below because I no longer see Resverlogix or Zenith on the presenting companies list. 

 

American Society for Nephrology (ASN) Kidney Week: Nov 5-10, 2019; Washington, D.C. 

November 8th: 1048: Apabetalone Lowers Serum Alkaline Phosphatase in CVD Patients with and Without CKD and Improves Cardiovascular Risk

November 8th: 317: Association of Serum Alkaline Phosphatase with CKD and Cognitive Function in Patients with Diabetes and Acute Coronary Syndrome

November 9th: 782: Apabetalone Downregulates Alkaline Phosphatase and Improves Cardiovascular Risk

  

American Heart Association (AHA): November 16-18, 2019; Philadelphia, PA. The full detailed results for the BETonMACE primary endpoint will be presented by Dr. Kausik Ray on Nov 16th at the late breaking clinical trial presentation. Plus, another alkaline phosphatase presentation on Nov 18th. Abstracts currently embargoed.

November 16th, 11:42-11:50 AM. Effect of BET Protein Inhibition With Apabetalone on Cardiovascular Outcomes in Patients With Acute Coronary Syndrome and Diabetes - Results of the BETonMACE Trial

November 18th, 11:30-12:00 PM. ALP Levels Predict Adverse Cardiovascular Outcomes and Cognitive Impairment in High Risk Patients

 

Clinical Trials on Alzheimer's Disease (CTAD): December 4-7, 2019; San Diego, CA. Two presentations in the final program on Thursday Dec 5th during the symposium on "Epigenetics and the BET-system in vascular dementia, Alzheimer’s disease and mixed dementia – the problem and potential remedies." One of them is the BETonMACE cognition sub-study presented by Dr. Jeffrey Cummings. A top-line statement on the cognition sub-study results might come ahead of CTAD.

PRESENTER 3: The epigenetic inhibitor APABETALONE corrects pathophysiological brain endothelial and microglial cell activation that contributes to neurodegenerative disease Ewelina Kulikowski, SVP Research and Development, Resverlogix Corporation, Calgary, Canada

PRESENTER 4: Epigenetics, the BET-system, Alzheimer’s Disease and Vascular Cognitive Impairment; The BETonMACE study and effects of apabetalone 100 mg b.i.d. two years treatment on cognition in diabetes patients with established cardiovascular disease Jeffrey Cummings, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA

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