"My reading of the data is that there was a significant difference between the treated and placebo groups in the CF change from baseline by the end of the study, and there was also a trend for CF to improve relative to baseline, but no stats were presented for the latter (which presumably means it was not significant)."

In my opinion, the vs. baseline change must be statistically significant. If the vs. placebo ~2 point change was statistically significant at end of study, then the vs. baslien ~4 point change would undoubtebly also be statistically significant.

BDAZ