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Message: Re: 4-8b guess - Is someone asking too much?
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Dec 08, 2019 08:38PM
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Dec 08, 2019 10:14PM
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Dec 08, 2019 10:22PM
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Dec 09, 2019 01:01AM
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Dec 09, 2019 02:15AM

"Imagine if the patient of the MoCA < 22 had the same number as MoCA >=26, 86 for ABL and 101 for placebo. Would we have gotten the same results of 158% relative improvement in cognitive function over the top standard of care placebo with statistical significance P-Value of 0.02? Was the MoCA <22, with 30 patients of ABL and 45 on placebo powered enough to prove absolute efficacy?"

Regardless, the cognition sub-study was only an exploratory study, never designed to support regulatory approval for a stand alone cognition indication. 

BDAZ

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