Re: 4-8b guess - Is someone asking too much?
in response to
by
posted on
Dec 09, 2019 11:13AM
"Imagine if the patient of the MoCA < 22 had the same number as MoCA >=26, 86 for ABL and 101 for placebo. Would we have gotten the same results of 158% relative improvement in cognitive function over the top standard of care placebo with statistical significance P-Value of 0.02? Was the MoCA <22, with 30 patients of ABL and 45 on placebo powered enough to prove absolute efficacy?"
Regardless, the cognition sub-study was only an exploratory study, never designed to support regulatory approval for a stand alone cognition indication.
BDAZ