I can see a certain logic to this...

Get the bad news out of the way first with Top-Line failure.

Then comes some encouraging news on cognition, but with a big grain of salt considering the incredibly small numbers involved in those where 208 showed promise. 

Finally (assuming BDZ is right and I hope he is) trumpet some truly significant news on the CKD front with big improvement in eGFR.  

From bad, to so so, to great.