If I may chime in, I think the statement "we're applying for breakthrough therapy status...."

I think this statement is too ambigious, especially when considering its Resverlogix we're talking about, with a long history of less than precise language in corporate communications.  Recall that it was previously communicated that there would be both and FA and later a SSRA conducted, but neither took place.

On the surface, "we're applying" suggests to me a continuing action in the present tense.  That is to say, its something that they were engaged at the time the statement was made.  I think of it in terms of being in the car and answering a call from someone asking what you and your wife are doing:  "we're heading home".  

Of course with Resverlogix its probably more like asking a teenaged son parked in front of a computer game about the homework that needs to be done:  "I'm doing my homework" he says.  What the teenager actually means is that he "will" do it later...maybe, he intends to do it, but maybe something will happen in the game that might stop him....yeah probably.

With resverlogix even definitive statements should be taken with a grain of salt in my opinion.