...sorry, my last post on this topic. It turns out I forgot some of my older posts. Specifically, Farxiga (Astra Zeneca). It is an SGLT2i, and it was halted early due to overwhelming efficacy for both T2D patients and non-T2D patients (I think it was then approved??? could be wrong). Any way, it is NOT recommended for patients with eGFR < 45, and it is "contrindicated" for patients with eGFR < 30. I think we would blow them out of the water in both MACE for ALL CKD patients (both T2D and non-T2D), AND we would be especially helpful in patients with eGFR < 45. AZN needs to take out RVX
https://twitter.com/GideonHealth/status/1244546213095112704
https://www.astrazeneca.com/media-centre/press-releases/2020/farxiga-phase-iii-dapa-ckd-trial-will-be-stopped-early-after-overwhelming-efficacy-in-patients-with-chronic-kidney-disease.html