Re: New RVX Tweet
posted on
Jul 31, 2020 09:44AM
Jon and others, question
Apabetalone reduces circulating ACE2 protein levels in patients, and downregulates ACE2 gene transcription by 40-90% in vitro
Do we know how long it takes to reduce ACE2 receptors once treatment starts? Remember in early 13 week test it was 4 to 5 weeks before usable HDL cells began showing. Not much help with Type2 and COVID-19. They may not have that much time. Just my thought, (could be all wrong), if test begins when Type 2 patient shows signs of COVID, will ABL have the desired affect, if ABL takes time to ramp up?
This is for our sicentists, I have no idea, just questions. Thanks, sidebar.
Another thought, if ABL does take 4 to 5 weeks and shows signs of benefit, seems to reason Type 2 should begin ABL treatment before exposure to COVID. Benefit to RVX now.