"Replacing stroke with CHF is the tweaking that has been done in the BoM2 trial along with the number of CKD patients. In theory the BoM2 numbers should be more than adequate to pass."
Don't forget that BoM2 is also planning to increase the number of patients on SGLT2i from ~12.5% in BoM to an estimated 70% in BoM2.
BDAZ