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Message: Trial design issues

One point which probably needs to be factored in here is Don said that due to the emergency nature of CoVid many jurisdictions would not wait for ph3 to use Apabetalone on an emergency basis if ph2 looked very good (use your own measure of salt, but in this case I think he may be correct). To me if this is the case an open label ph2 is the probably the quickest way to get a first look. 

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