Hospital seeks emergency approval of Israeli COVID drug for moderate-seriously ill

In letter to Health Ministry director, Ziv Medical Center points to promising results from Amor 18’s clinical trial, where all patients who received drug went on to recover

https://www.timesofisrael.com/hospital-seeks-emergency-approval-of-covid-drug-for-moderate-to-seriously-ill/

In the first stage conducted at Ziv, Be’er Yaakov’s Assaf Harofeh and Tel Aviv’s Ichilov Hospital all patients who received the drug, which is either inhaled or taken under the tongue, went on to recover from COVID-19 and were released from the hospital

In the second phase of the trial, Ziv Medical Center recruited 37 patients in moderate-to-severe conditions to participate. Eighteen of them were given Amor 18 and 19 received a placebo.

All the patients who received Amor 18 recovered and were discharged several days later. Of the 19 others, six of them saw their condition deteriorate and had to be transferred to the ICU. Two of those patients died.

Dr. Nashat Abu Saleh, who heads the geriatrics department at Ziv Medical Center told Ash in the letter that two patients in critical condition who didn’t qualify for the trial were also given Amor 18 through compassionate use. Both of them saw their subsequent conditions significantly improve and were later released from the hospital.