We are now, evidently, 3 weeks into dosing at UofA.  There should now be some very initial indications as to impact on a patient and/or patients.  If we get notice, say, next week on the commencement of dosing at additional sites do we take that as a positive indication of efficacy?  Or, does the prolonged delay of dosing at other sites suggest otherwise?  I would think we'll have our answer soon whatever way this goes.