Very interesting that you say that golf because that thought has been on my mind for a while.

• Was there really a n=10,000 patient, 5 year trial discussed that RVX turned down? If they had proceeded we'ed be almost half way through with possible early results now.

Also, if Don really has spoken to BPs why can't he give us an overview and update of his progress and barriers at this stage. There is nothing confidential about such information so why can't he talk about these things?

Toinv