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Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

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Message: Re: AACR
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Mar 30, 2019 06:07AM
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Mar 31, 2019 08:05AM
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Apr 01, 2019 02:39PM
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Apr 01, 2019 05:52PM

"BDAZ - What is ZEN-3791? I don't remember ever hearing about that in the past."

It sounds like ZEN-3694 is metabolized to ZEN-3791, the latter of which is the "active" metabolite. I think the term for this is pro-drug, in which ZEN-3694 needs to be converted to a different form in the cell to become the active molecule. First I've heard of that for ZEN-3694.

BearDownAZ

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Apr 01, 2019 08:25PM
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Apr 08, 2019 11:46AM
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Apr 09, 2019 11:36AM
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