BET inhibitors induce senolysis

...We Welcome You to the Zenith Epigenetics Hub withIn The AGORACOM COMMUNITY!

Zenith's BET Inhibitor ZEN-3694 is Currently Being Evaluated in Multiple Oncology Clinical Trials

Reply New Message

Prev Message Back To Forum Threaded View Next Message

BearDownAZ

Rank: President [?]

Points: 25003 [?]

Votes: 68 Score: 4.5 [?]

Your Vote:

Please Log In to Vote

Did you know? You can earn activity points by filling your profile with information about yourself (what city you live in, your favorite team, blogs etc.)

BET inhibitors induce senolysis

posted on Apr 23, 2020 07:54AM

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

https://www.nature.com/articles/s41467-020-15719-6

They looked at a few different BET inhibitors, but none from Zenith or Resverlogix. Still, this adds some potential insight into the benefits of BET inhibitors.