It looks like one of the NCI trials has been discontinued due to unacceptable toxicity.
The trial was in Phase 1 for advanced or unresectable solid tumors with RAS alternations or TNBC, in comination with Binimetinib.
https://clinicaltrials.gov/ct2/show/NCT05111561
Another trial was suspended, "to address important protocol updates". Not sure what that means.
https://clinicaltrials.gov/ct2/show/NCT05372640?term=zen-3694&draw=3&rank=12