TORONTO, ONTARIO--(Marketwire - June 22, 2010) - MacDonald Mines 
Exploration (TSX VENTURE:BMK) ("MacDonald" or "the Company") announces the 
results from the spring 2010 drill program on its McNugget Property located 
in the Ring of Fire, James Bay Lowlands.

The 26 hole, 4,471 meter drill program consisted of a series of holes 
designed to test electromagnetic ("EM") anomalies on three fold limbs 
associated with sequences containing volcanogenic massive sulphide (VMS) 
mineralization of substance (as described by Hadyn R. Butler, P.Geo) and 
having characteristics similar to the Matagami or Noranda VMS camps in 
Quebec, where larger VMS deposits with satellite deposits along strike were 
found. This conclusion is also supported by C. Tucker Barrie PhD, P.Geo 
who, accompanied by the Company's Vice President of Exploration Quentin 
Yarie, P.Geo, has just completed a comprehensive on-site review of previous 
nickel and VMS drill core and exploration data. The historical production 
and resource from the Matagami Camp was 25 million tonnes grading 0.56% 
copper, 8.2% zinc and 20.91 g/t silver.

The Company is very encouraged by this large VMS system which is open in 
all directions and yields VMS mineralization over a potential cumulative 
strike length of approximately 20 kilometres. Upcoming drilling will focus 
on finding the best economic intersections along the VMS horizons. As noted 
in the Company's recent news releases, many other EM targets found during 
this winter/spring's revised data compilation will also be subject to 
follow-up prior to drill target selection.

Assay Highlights 

Highlighted base metal results from this completed phase of drilling are 
summarized in tables at the end of this release with full assay results 
available at www.macdonaldmines.com. A summary of these highlighted drill 
holes are as follows and note that holes MN10-102 and MN10-104 contain 
copper, zinc and silver values within the same intersection.

/T/

Copper (Cu)                                                                 

--  Hole MN10-102 intersected 1.03% over 15 metres 
--  Hole MN10-111 intersected 1.04% over 5 metres 
--  Hole MN10-90 intersected 1.11% over 5 metres 

Zinc (Zn)                                                                   

--  Hole MN10-104 intersected 3.3% over 9 metres 
--  Hole MN10-106 intersected 2.55% over 4 metres 
--  Hole MN10-110 intersected 2.82% over 5 metres 
--  Hole MN10-102 intersected 2.5% over 3 metres 
--  Hole MN10-104 intersected 2.00% Zn and 0.88% Cu over 6 metres 

Silver (Ag)                                                                 

--  Hole MN10-87 intersected 13.32 g/t over 5.3 metres 
--  Hole MN10-94 intersected 16.57 g/t over 4 metres 
--  Hole MN10-102 intersected 11.67 g/t over 3 metres 
--  Hole MN10-104 intersected 11.97 g/t over 3 metres 

/T/

Crone Geophysics Interprets Fourth VMS-Mineralized Limb 

On-going data compilation has established that a fourth mineralized fold 
limb occurs on the McNugget Property striking southeast. During the spring 
work program, MacDonald surveyed previous drill holes on the fourth limb 
with the Crone Geophysics down hole pulse EM system. This technique proved 
invaluable at locating targets that were unexplained in previous 
exploration programs. This approach was used to locate borehole MN10-104.

MN06-18 and MN06-17 (drilled in 2006) were also geophysically probed. The 
interpretation of these data suggests a target with similar characteristics 
as those of MN10-104 - a conductive, steeply dipping sheet. Based on the 
borehole geophysics, a surface EM survey is being completed over the target 
(to be drilled during the next phase of exploration). 

Quentin Yarie, P. Geo, Vice President of Exploration comments, "This target 
on the newly identified fourth mineralized fold limb was not previously 
seen by the earlier VTEM survey. The conductance is quite high and it 
appears to have some strike length with the top of it being rich in Zn, 
followed by Cu. We are in the process of mapping it, as we know the results 
from MN06-17 had significant Zn and silver (Ag) numbers".

MN06-18 intersected 6.99m of 0.59% Cu, 2.70% Zn, 17.59 g/t Ag including a 
2.79m intersection of 5.21% Zn. Of particular interest in this hole is the 
build up to a late time, long wavelength off-hole anomaly representing a 
deeper conductor which has never been tested. This represents an exciting 
new target and preliminary modeling results indicate the potential here for 
a large, high conductance source. MN06-18 is located approximately 700m 
east of the "North Fold limb" noted in Macdonald's press release dated 
5/31/2010.

Nickel Target Identified on MacDonald and Hawk Uranium Joint Venture Ground

MacDonald Mines has completed a surface Crone Geophysics Pulse EM survey 
over a highly prospective nickel (Ni) target in the vicinity of borehole 
MN06-39 (27m averaging 0.17% Ni including 1m intersections of greater than  
0.5% Ni). Preliminary interpretation indicates a step response of a 
conductive body trending approximately East-West with a strike length of 
over 300m which is currently being modeled. A second conductor may exist 
under one of the loop edges. The surface program is being widened with a 
different transmitter loop location to assist in the resolution of both 
conductors prior to drilling of this target in the summer of 2010.

Further assay results

Fire assays for gold (Au) content are pending on all holes drilled during 
the spring program.

On-site Quality Assurance/Quality Control Measures 

All diamond drill (half core) samples were collected and sealed on site and 
shipped under chain of custody supervision to the ACTLABS sample 
preparation laboratory in Thunder Bay, Ontario. Analyses are performed by 
ACTLABS laboratories (ISO/IEC 17025 certified) either in Ancaster or 
Thunder Bay, Ontario. All core samples were selected by the MacDonald Mines 
qualified site geologist, and were cut in half on site by diamond saw. For 
security, the remaining half core was then resealed in the original core 
boxes. Individual half core samples were labelled, placed in plastic sample 
bags and sealed. Groups of samples were placed into sealed and durable rice 
bags then shipped out by air transport. Remaining coarse reject portions of 
all samples remain in storage at the ACTLABS preparation laboratory storage 
facility at Thunder Bay.