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Message: Pharmacological targeting of BET proteins inhibits renal fibroblast activation

Title contn'd: ...and alleviates renal fibrosis

I am not sure this paper got the attention of this board, but in any case, it provides highly relevant evidence supporting RVX-208's claim as a renal drug. It does, btw, also mention that Brd4 inhibition blocks NF-kB (please read the Seeking Alpha articles on Resverlogix for background info on NF-kB).

Here is the link to the paper referenced above:

http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=12498

/B.

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