Does anyone have an opinion about if the primary 3 point MACE endpoint is significant but only at the 90% confidence level (95% required) but the combined 5 point MACE results replicate the combined results from the post hocs i.e. 77% RRR and are highly statistically significant?

My opinion is that this would be similar to June of 2013 - "apabetalone failed to achieve it's primary end pont" and many of us know what happened then.

And yet, as we saw from the post hocs apabetalone is still alive and well.

Thoughts.

Toinv