Re: MACE Events - Statistically Confusing
in response to
by
posted on
Mar 01, 2019 08:59AM
"Imagine if the stock halted and your quote system went down and Bear was on vacation in the Himalayas and could not post, would you have a clue if the stock was going to explode or tank?"
I guess I should get a passport. I've been to Canada and Mexico before, but not in a while. I couldn't cross either border legally anymore!
In a prior post, Koo wrote "In [other] words, this, in essence, could this simply be a horse race between the apabetalone and placebo groups as to which group ends up with least number of MACE event up to the time when 250 MACE events are reached in totality with no consideration to when they occur from the start date to the end date of the trial, the trial being event-based. So the "primary outcome measure" is calculated as a percentage on this basis. Why would it need to be more complicated than that? "
I added the bolding and underlining. My best advice to those confused about the time factor and the need for survival curves and Kaplan-Meier analysis is to do some due diligence. Google. PubMed. Wikipedia. Etc. I provided some links below. I'm sure there are some tutorial videos too.
BearDownAZ
Understanding survival analysis: Kaplan-Meier estimate
The analysis of survival data: the Kaplan–Meier method
Wikipedia Kaplan–Meier estimator
Why Use a Kaplan-Meier Analysis
A PRACTICAL GUIDE TO UNDERSTANDING KAPLAN-MEIER CURVES