Yes, that second video is a joke....and I laugh at it as well, 'anywhere you find the production of minfletranions'.  

As for dumbing down Apabetalone, the way I break it down for my feeble brain is this....Apabetalone attaches itself at the level above the genetic, at the Epigenetic level....there it reads whether that incredibly small portion of DNA/RNA (or whatever NA) is in an open or closed position, whether its on or off....off meaning a diseased state, on being non-diseased.  If its off Apabetalone recruits proteiens which turns the switch from off to on, from diseased to non-diseased.

I know that is overly simplistic and I dodn't have all the terms down....but ostensibly its like a mechansim turning a switch.