Fuzz, nice job getting that response from IR, it is the most informative I have seen from this company. They should endeavour to maintain that kind quality and timelines in all their communications. I sure wish, as most others I think, that they would address the the reasons for the dosing being delayed for so long. To me it only stands to reason that when the CEO makes numerous completely erroneous statements regarding any particular subject that the company then follows up with statements to clarify why he was so far off. Who knows perhaps there have been a series of events that have reasonably delayed the start. Whatever the reason address it, that would seem to be the easiest way to keep shareholders on board and thus support the share price at least somewhat. What the market dislikes the most is uncertainty yet it seems Don's greatest talent is creating uncertainty. Pretty sad that this company, with all its positive science, trades at a value roughly equivalent to it's tax loss value as a complete write off. Especially when a little proactive communication and investor expectation management could go a long way to remedying this.