The high RRR % in all those phase 2 trials was for 5 Point MACE,.. with very few of the the 3 Point events we eere testing in the primary endpoint.

They only aimed for 30% RRR in the combined group, which the previous three trials exceeded in post-hoc.

I can easily imagine such strong post-hoc numbers in one of the Phase 2 trials being a fluke, but somehow it seems less likely to have been a fluke when all three of them showed such strong results. Don had noted at one point that the BETonMACE trial was only powered at 80% for a 30% RRR...but i think they were expecting that beating 30% would be a non-issue.