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"Why 60? Why not look at it differently and ask, what eGFR threshold must be passed before RRR goes below, say, 30%? It's hard to believe that there's a sudden change, right at 60, from fantastic to insignificant...."
Because the above and below baseline 60 was the pre-specified cut off for the subgroup comparison at the start of the trial. And because the CKD sub-study was pre-specified as those with baseline eGFR below 60. This was all set over four years ago.
