Bear,,my bad head again,,the original 125 event accumulation was what i was thinking but the new 250 came out,,,my apologies,,,so do you think we have had the 125 events pre Decemeber 31, 2017?,,it seems the increase to 250 events was made public possibly near the timing we expected the FA from a 125 particpant event. What should an investor read into these timings and numbers? Was the original 125 events determined to be the average expected events from the dosing of the anticipated enrollement numbers if there was no effect from the use of 208?..it would seem that it would be a smart move to have the 125 number based on data in early for the FA so that the trial could be terminated early eliminating wasting $$$ and essential services if we knowingly are barking up the wrong tree here..just an opinion.