PH - It might be just a little more complicated  than you are thinking. The 30% RRR reduction with 80% power was for 2400 patients with a total of 3600 patient years of dosing to get 250 events to achieve that statistical significance with 80% power. We had 2425 patients that went a little bit longer than the anticipated 18 months on average, likely having more than 3600 patient years. There seems to be a few more than 250 events (we'll know the exact number soon) so we may find that statistical significance will be achieve with less than 30%RRR. It would be best if someone with medical stats experience could step in here as I am now over my head.

tada