"I don't really follow that argument, Bear. In which of those two scenarios, and why, would you think animal experiments are necessary, and in which one would they not be necessary?"

My thoughts were that if going after an anti-viral mechansim, this is a new area for apabetalone that would benefit from having some animal data first. But if going after treating side effects of severe coronavirus infection, that their previous animal/human data on inflammation/acute phase response/cardiopulmonary endpoints would be sufficient proof of concept to forego additional animal data.

BDAZ