Re: BET inhibitor and BRD4 papers keep piling up
in response to
by
posted on
Sep 25, 2017 09:24PM
Nice post (and nice discussion). Thanks.
I have been wondering about RVX-208 and insulin resistance.
I did find "RVX-208 delayed and reduced oral glucose absorption and endogenous glucose production, with plasma glucose maintained via reduced peripheral glucose disposal. If sustained, these effects may protect against the development of type 2 diabetes."
But not sure that really counts as reduced insulin resistance.
Been reading about dementia/alzheimers as "Type III Diabetes" - mediated by insulin resistance in the brain.
Has anyone seen anything more specific on RVX-208 and insulin resistance?
(Apologies if i missed it - still reading replies to this post)